Integrins: A role for adhesion molecules in olfactory memory

Glycobiology of the olfactory system.

The olfactory system is a highly plastic region of the nervous system. Continuous remodeling of neuronal circuits in the olfactory bulb takes place throughout life as a result of constant turnover of primary sensory olfactory neurons in the periphery. Glycoconjugates are very important in olfactory development, regeneration and function. This article deals with different aspects of glycobiology...

Activity-Dependent Regulation of Synaptic AMPA Receptor Composition and Abundance by β3 Integrins

At synapses, cell adhesion molecules (CAMs) provide the molecular framework for coordinating signaling events across the synaptic cleft. Among synaptic CAMs, the integrins, receptors for extracellular matrix proteins and counterreceptors on adjacent cells, are implicated in synapse maturation and plasticity and memory formation. However, little is known about the molecular mechanisms of integri...

P27: KCNK2 and Adhesion Molecules in an in-Vitro Blood Brain Barrier Model

Two-pore domain potassium channels, like KCNK2, are known to play an important role in inflammatory diseases such as multiple sclerosis (MS). Upregulation of cellular adhesion molecules in mouse brain microvascular endothelial cells (MBMECs) of Kcnk2-/- mice resulted in elevated leukocyte trafficking into the central nervous system under inflammatory conditions. The current project aims to gain...

Signal transduction and signal modulation by cell adhesion receptors: the role of integrins, cadherins, immunoglobulin-cell adhesion molecules, and selectins.

Effect of one Bout Continuous Versus Intermittent Aerobic Exercise on Plasma Levels of Intercellular Adhesion Molecules 1 and Vascular Cell Adhesion Molecules 1 in Patients with Coronary Heart Disease

Introduction: Adhesion molecules play an important role in the pathogenesis of atherosclerosis and the type of training may affect the response to these indicators. Therefore, the purpose of the present study was to investigate the effect of a continuous versus interval aerobic training session on plasma levels of intercellular adhesion molecules 1 (ICAM-1) and vascular cell adhesion molecules ...